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UK Critical Care Research Group

Advancing Critical Care Worldwide

UKCCRF25


Manchester


September 16th - 17th, 2025

This is the 15th national forum for clinical research in critical care, emergency medicine and acute medicine, hosted by Dr Jonathan Bannard-Smith

The meeting will include sessions on:
- International collaborations in clinical trials
- Clinical Trials - Lesser known components
- Health Services Research
- Experimental Medicine


UK Critical Care Research Groups

We are updating the UKCCRG website.

Please share the details of your critical care research group. You can do this via:

(1) the QR code

or

(2) https://redcap.link/UKCCRG

or

(3) email This email address is being protected from spambots. You need JavaScript enabled to view it.

Welcome to the
UK Critical Care Research Group

A warm welcome to the UKCCRG website. The United Kingdom Critical Care Research Group (UKCCRG) represents those involved in conducting research in the critically ill in the United Kingdom. We embrace all research studies, from basic science and experimental to clinical trials and health services research. The group was convened in 2010 and has evolved to become the critical care research studies and trials group of the UK. Our mission is to improve patient outcomes by developing new treatments, testing innovative ways to improve care delivery, and by identifying better ways to translate knowledge into practice. We are dedicated to advancing practice through high quality research.

Prof Bronwen Connolly

Chair UKCCRG

Ongoing Major Trials

  • AWARE II
    AWAreness during REsuscitation
  • COMBACTE ASPIRE-ICU
    Staph Aureus & Pseudomonas Infections
  • A-STOP
    Antifungal Stewardship
  • COMPRESS-RCT
    Mechanical Chest Compression in Cardiac Arrest
  • PRACTICE
    Ventilatory weaning in paediatric ICU
  • REMAP-CAP
  • UK-ROX
    Oxygenation targets in mechanically ventilated patients
  • MARCH
    Mucolytics in critically ill patients
  • MOSAICC

Recently Completed Trials

  • ADAPT-SEPSIS
    Biomarker-Guided Duration of Antibiotics
  • A2B
    Alpha 2 Agonists for Sedation
  • STRESS-L
    Beta Blockade in Tachycardic Sepsis
  • SANDWICH
    Sedation and Weaning in Children
  • REST
    ECCO2R in Respiratory Failure
  • 65
    Permissive Hypotension (MAP 60-65 mm Hg) in Shock
  • POPPI
    Nurse delivered psychological support in the ICU
  • SUP-ICU
    PPI therapy for stress ulcer prophylaxis
  • PEPTIC
    PPI vs H2RB for Stress Ulcer Prophylaxis
  • STARRT-AKI
    Initiation of RRT in Acute Kidney Injury